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Crocin II
CAS No. 55750-84-0
Crocin II ( —— )
产品货号. M18809 CAS No. 55750-84-0
藏红花素对大鼠胃缺血再灌注损伤具有抗炎和抗凋亡作用，藏红花素的作用主要是通过降低iNOS和caspase-3的蛋白表达来介导。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥778 | 有现货 |
|
| 10MG | ￥1337 | 有现货 |
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| 25MG | ￥2584 | 有现货 |
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| 50MG | ￥3880 | 有现货 |
|
| 100MG | ￥5573 | 有现货 |
|
| 500MG | ￥11502 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Crocin II
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述藏红花素对大鼠胃缺血再灌注损伤具有抗炎和抗凋亡作用，藏红花素的作用主要是通过降低iNOS和caspase-3的蛋白表达来介导。
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产品描述Crocin has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, crocetin, can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.
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体外实验——
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体内实验——
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同义词——
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通路Metabolic Enzyme/Protease
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靶点Lipid
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受体Others
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研究领域Others-Field
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适应症——
化学信息
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CAS Number55750-84-0
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分子量814.83
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分子式C38H54O19
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 25 mg/mL (30.68 mM)
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SMILESC(=O)(/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C(=O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)\C)\C)/C)/C)O[C@H]1[C@@H]([C@@H]([C@@H]([C@H](O1)CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O)O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Lee IA,et al. Antihyperlipidemic effect of crocin isolated from the fructus of Gardenia jasminoides and its metabolite Crocetin. Biol Pharm Bull. 2005 Nov;28(11):2106-10.
